Healthcare for Ocular Surface Diseases in Canada

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Content warning: suicide

The state of healthcare for ocular surface diseases (OSDs) in Canada is in crisis. While a range of treatment options exist, none are covered by provincial health systems, and they are rarely covered by private insurance plans. Most Canadians with severe OSDs struggle to afford the treatment they require.

Lives are at stake. There are two documented cases of suicide in Canadians suffering from ocular surface diseases.


Neuropathic Corneal Pain: the inaccessibility of diagnostic testing and expert knowledge

Neuropathic Corneal Pain is recognized in Canada as a disease separate from other ocular surface disorders1. However, the range of available diagnostic tools and treatment options are failing to adequately meet the needs of Canadians suffering from this condition.

While there is no available data on the prevalence of NCP, we estimate that it impacts a few thousands Canadians.

NCP can be challenging to diagnose without the use of a confocal microscope to image the nerves of the cornea2. Unlike an eye care provider’s slit lamp, a confocal microscope is able to detect nerve abnormalities on the cornea. Without it, ophthalmologists are only able to offer a speculative diagnosis of exclusion, and patients are often misdiagnosed or told that the pain is all “in their head”3,4.

Canadian eye care providers are unable to access confocal microscopes to diagnose their patients. As a result, Canadian patients must travel to clinics in the United States equipped with a confocal microscope to receive a clinical diagnosis of NCP.

Most provinces offer a program where a doctor can apply to have their patient receive provincial funding to obtain a medically-necessary health service abroad that is not available in Canada (for example, see Ontario’s Out of Country Prior Approval Program). These programs sometimes fund patients who need to visit an ophthalmologist in the U.S. to receive a confocal scan. Programs only cover pre-approved tests at the American clinic, and do not cover any travel costs. Patients are generally only accepted if they have an extensive history of eye treatments within Canada with little improvement in symptoms3. This means Canadians need to have already spent an exorbitant amount of money on health care at home. Moreover, the difficulties of traveling with this condition, as well as financial barriers, are often prohibitive.

While confocal microscopes exist at many Canadian universities and hospitals, ophthalmologists treating patients do not currently have access. There is no reason that Canadians should need to travel abroad to access technology that exists in Canada but is merely inaccessible.

According to Dr. Pedram Hamrah, the leading specialist in the treatment of NCP, early detection and treatment are key in achieving a positive outcome4. The lack of accessible diagnostic testing is reducing Canadian NCP patients’ chances of a complete recovery, and is prolonging their suffering.


Exorbitant costs of treatment

Available treatment options are currently not covered by most provincial health care plans or private insurance plans, despite their proven efficacy2. As a result, Canadian OSD patients must pay out-of-pocket for essential treatments.

OSDs can be disabling diseases, and if left untreated they prevent most patients from working full-time, leaving many unable to afford the care they need,3,5. Treatments are only financially accessible to those with substantial savings or family willing to help cover the costs.

The table below lists treatments for OSDs and average costs in CAD:


Table 1. Treatments and diagnostic tests for ocular surface diseases available in Canada and their costs as of 2022. Information on treatment costs were reported by Canadian patients on the Neuropathic Corneal Pain and Corneal Neuralgia Patients Facebook Group. All prices are in CAD.

Treatment Cost Description

Autologous Serum Drops

$210
Up to a year’s supply (depends quantity of blood drawn)
Eye Institute, the Ottawa Hospital


$200 - $235
2-3 month supply
People’s Choice Pharmacy, Richmond Hill


$235
3 month supply
Haber’s Pharmacy, Toronto


$190
4 month supply
Premium Vision Surgical Centres, Cornwall



Eyedrops made from a patient’s own blood serum. Serum drops contain growth factors that help heal defects on the corneal surface and corneal nerve abnormalities.

Platelet-Rich Plasma Drops

$425
1 month supply
Uptown Eye Specialists
Greater Toronto Area


$350
6 week supply
Lip Doctor
Mississauga



Eyedrops made from a patient’s own blood. Similar to autologous serum drops, but contains a higher concentration of growth factors.

Prosthetic Ocular Surface

$10,500 (approx.)
PROSE
Precision Cornea Centre, Ottawa


$10,000 (approx.)
Eye Print Pro
Vaughan Family Vision Care, Vaughan



A custom-fit specialty lens that acts as a prosthetic eye surface. They protect the sensitive or injured cornea from environmental triggers.

Scleral Lenses

$3100
Zen lens
Kensington Eye Institute, Toronto


Rigid contact lens that sits on the sclera, filled with liquid saline solution. They protect the cornea from environmental triggers. Similar to prosthetic ocular surfaces, but less customizable. Often unsuitable for severe cases of OSDs.


Intense Pulsed Light (IPL)

$300 - $400
Per session
Various optometry and ophthalmology clinics


IPL stimulates the meibomian glands to produce more meibum, a vital component of a healthy tear film.

Maintaining a stable tear film is an essential component of treating most OSDs.

Most patients require a minimum of 4 sessions, with some patients requiring upwards of 20 IPL sessions.


Intraductal Meibomian Gland Probing

$400-$1000
Per session
Various optometry and ophthalmology clinics


A procedure which breaks up scar tissue in blocked meibomian glands and widens the opening of each gland. Blocked and dysfunctional meibomian glands are the dominant cause of dry eye disease.


Amniotic Membrane (e.g., Prokera)

$1100 - $1300
Eyes on Sheppard, Toronto

A treatment used to heal damage on the surface of the eye, reduce inflammation, and promote nerve regeneration. An amniotic membrane, a tissue rich in stem cells and other healing factors taken from a placenta, is placed on the eye and left for several days to weeks.


Dry eye testing (e.g., schirmer’s, meibography)

$150 - $200
Various optometry and ophthalmology clinics

Dry eye testing is used to assess the severity of various factors contributing to the disease..

Lack of funding for special access programs

Ontario provides limited funding to cover the costs of PROSE lenses for qualifying patients at the Kensington Eye Institute in Toronto. A patient and their doctor must apply to this program. However, the program almost never accepts dry eye and NCP patients, and it appears to prefer funding patients with visible eye damage or irregularities and sight-impairment.


Challenges for Ophthalmologists

Eye care providers also face barriers which prevent them from providing essential care to their patients. In a 2018 survey of Canadian ophthalmologists, half of respondents reported that autologous serum tears are inaccessible to their practice due to financial and logistical barriers. Insufficient reimbursement for providing the service was reported as a major detractant. 68% of ophthalmologists stated they would prescribe serum tears to their patients if they were more accessible6.

Results from this study reinforce the fact that there are significant disparities in terms of access to essential healthcare for ocular surface disorders. Not only is autologous serum financially inaccessible to many patients, many of their doctors are unable to even offer it to their patients who require it.


Quebec: better, but not good enough

Quebec’s healthcare system covers the costs of autologous serum tears and prokera if they are prescribed by ophthalmologists employed with a hospital. However, accessing these treatments is notoriously challenging. Quebecois patients report that doctors are discouraged from prescribing serum tears, and that finding one willing to do so is extremely difficult3.


Terminological overlap with other industries

It is important to distinguish between the essential treatments offered by eye care professionals to treat serious eye diseases, and the elective procedures in the cosmetic industry that have an unfortunate overlap in terminology.

Intense pulsed light (IPL) is used in ophthalmic care to stimulate the meibomian glands to produce more meibum, a vital component of a healthy tear film. Improving the quality of tear film is an essential component of treating most OSDs

Autologous serum tears (AST) and platelet rich plasma (PRP) are eyedrops made from a patient's own blood that assist in healing defects on the ocular surface and corneal nerve abnormalities.

IPL, AST, and PRP are also used for skincare treatments in the cosmetic industry. The overlap in terminology between skin rejuvenation procedures and ophthalmological treatments have further inhibited OSD patients from accessing adequate funding for these essential treatments. Provincial health insurance programs and private health insurance plans may be under the false impression that these treatments offered in an ophthalmological setting are elective and cosmetic.


Why provincial governments should care

With the lack of recognition and funding for OSDs, the provinces are currently violating their obligations under the Canada Health Act, which exists “to protect, promote and restore the physical and mental well-being of residents of Canada and to facilitate reasonable access to health services without financial or other barriers”7. To meet their obligations under these acts, the provincial governments must improve the state of medical care for OSD patients.

It is also in the financial interest of the provincial governments to improve the state of healthcare for OSD patients. When not properly treated, OSD renders patients disabled and unable to work. When patients can access treatments, they become more functional and can resume full-time work, thus resuming an active role in society and the workforce. The provinces will directly benefit from supporting the healthcare of OSD patients who often rely on disability programs and social assistance to survive. Providing these patients with adequate access to treatments is more cost effective than having to support them on disability programs.




REFERENCES

1 Sklar, J. C., Thakrar, V., Stein, R., Caffery, B., Liao, J., & Chan, C. C. (2020). Management of patients with ocular neuropathic pain. Canadian Journal of Ophthalmology, 55(4), 342.

2 Dieckmann, G., Goyal, S., Hamrah, P. (2017). Neuropathic Corneal Pain: Approaches for Management. Ophthalmology, 124(11), S34-S47

3 Neuropathic Corneal Pain and Corneal Neuralgia Patients. (n.d.). In Facebook [Private Group]. https://www.facebook.com/groups/1713169018917451

4 Mukama, R. (n.d.). What Is Neuropathic Corneal Pain? National Organization for Rare Disorders. Retrieved January, 2022, from: https://www.aao.org/eye-health/symptoms/what-is-neuropathic-corneal-pain-2

5 Goyal, S., & Hamrah, P. (2016). Understanding neuropathic corneal pain—gaps and current therapeutic approaches. Seminars in ophthalmology, 31(1-2), 59-70.

6 Marchand, M., Harissi-Dagher, M., Germain, M., Thompson, P., & Robert, M. C. (2018). Serum drops for ocular surface disease: National survey of Canadian cornea specialists. Canadian Journal of Ophthalmology, 53(3), 266-271.

7 Canada Health Act (Canada). R.S.C., 1985, c. C-6. Last access January 2022, https://laws-lois.justice.gc.ca/eng/acts/c-6/page-1.html